Main Title |
Subchronic (3-month) Oral Toxicity Study in the Dog with Lx1106-01 via Capsule Administration (Final Report) with Attachments and Cover Letter Dated 04/24/1991 (Sanitized). |
CORP Author |
Bio-Dynamics Research and Development Corp., Eugene, OR.; Mobil Oil Corp., New York.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Year Published |
1991 |
Report Number |
86-910000808S |
Stock Number |
OTS0529440 |
Additional Subjects |
Toxicology ;
Health effects ;
Solvent Naphtha (petroleum) Light Aromatic (64742-95-6) ;
Subchronic Toxicity ;
Mammals ;
Dogs ;
Oral ;
Gavage ;
Toxic substances ;
Laboratory animals ;
CAS No 64742-95-6
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
OTS0529440 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
284p |
Abstract |
Solvent Naphtha, light aromatic (C8-10) (CAS No. 64742-95-6) was evaluated for subchronic toxicity. The test substance was administered to beagle dogs (4/sex/group) by a gelatin capsule in dose levels of 0, 125, 250, and 500 mg/kg/day, 7 days/week for 90 days. No deaths were noted. Body weights of treated animals were decreased (not statistically significant) at the end of the study as compared to controls. High-dose animals had borderline anemia. No effects were noted on the eyes, clinical chemistry, organ weights, organ/body weights, or gross and microscopy. |
Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with Mobil Oil Corp., New York. |
Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
PUB Date Free Form |
1991 |
Category Codes |
57Y; 57U; 68G; 99; 44G |
NTIS Prices |
PC A14/MF A14 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
028803090 |
Origin |
NTIS |
Type |
CAT |