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RECORD NUMBER: 856 OF 937

Main Title Subchronic (3-month) Oral Toxicity Study in the Dog with Lx1106-01 via Capsule Administration (Final Report) with Attachments and Cover Letter Dated 04/24/1991 (Sanitized).
CORP Author Bio-Dynamics Research and Development Corp., Eugene, OR.; Mobil Oil Corp., New York.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1991
Report Number 86-910000808S
Stock Number OTS0529440
Additional Subjects Toxicology ; Health effects ; Solvent Naphtha (petroleum) Light Aromatic (64742-95-6) ; Subchronic Toxicity ; Mammals ; Dogs ; Oral ; Gavage ; Toxic substances ; Laboratory animals ; CAS No 64742-95-6
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NTIS  OTS0529440 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 284p
Abstract Solvent Naphtha, light aromatic (C8-10) (CAS No. 64742-95-6) was evaluated for subchronic toxicity. The test substance was administered to beagle dogs (4/sex/group) by a gelatin capsule in dose levels of 0, 125, 250, and 500 mg/kg/day, 7 days/week for 90 days. No deaths were noted. Body weights of treated animals were decreased (not statistically significant) at the end of the study as compared to controls. High-dose animals had borderline anemia. No effects were noted on the eyes, clinical chemistry, organ weights, organ/body weights, or gross and microscopy.
Supplementary Notes The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with Mobil Oil Corp., New York.
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PUB Date Free Form 1991
Category Codes 57Y; 57U; 68G; 99; 44G
NTIS Prices PC A14/MF A14
Document Type NT
Cataloging Source NTIS/MT
Control Number 028803090
Origin NTIS
Type CAT