| Main Title |
Subchronic Inhalation Toxicity Study on Diglyme with Cover Letter dated 07/15/88. |
| CORP Author |
Du Pont de Nemours (E.I.) and Co., Wilmington, DE. DuPont Environmental Remediation Services.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
18 Jul 1988 |
| Year Published |
1988 |
| Report Number |
FYI-OTS-0788-0553; |
| Stock Number |
OTS-0000553-1 |
| Additional Subjects |
Toxicity ;
Ethers ;
Rats ;
Laboratory animals ;
Concentration ;
Indoor air pollution ;
Clinical chemistry analysis ;
Hematological analysis ;
Inhalation ;
Diethylene glycol dimethyl ether ;
Diglyme ;
2-methoxyethano1 (2-ME)
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0000553-1 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
448p |
| Abstract |
Three groups of 20 male and 10 female Cr1:CDBR rats were exposed nose-only, 6 hours/day, 5 days/week for 2 weeks to 110, 370 or 1100 ppm of diethylene glycol dimethyl ether (diglyme) vapor in air. A positive control group of 20 male and 10 female rats was exposed to 300 ppm of 2-methoxyethano1 (2-ME) vapor in air and a procedural control group of 20 male and 10 female Crl:CDBR rats was exposed to air-only. At the end of the 2-week exposure and the 14-day post exposure recovery periods, blood and urine samples were collected for hematologic and clinical chemical analyses from 5 male and 5 female rats per group; these rats were then killed for pathologic examination. The remaining male rats (2 groups of 5 rats per group) were killed after an extended recovery period of either 42 or 84 days post exposure and subjected to the same hematologic, clinical chemical and pathological examinations. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
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| Category Codes |
57Y; 68A; 57D |
| NTIS Prices |
PC A20/MF$25.00 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
019101050 |
| Origin |
NTIS |
| Type |
CAT |
