| Main Title |
Studies on the Flavor Aversions Induced by Trialkyltin Compounds. |
| Author |
MacPhail, R. C. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1982 |
| Report Number |
EPA-600/J-82-301; |
| Stock Number |
PB83-189555 |
| Additional Subjects |
Toxicology ;
Rats ;
Laboratory animals ;
Reprints ;
Heavy metals ;
Trimethyltin ;
Triethylin ;
Flavor aversions
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB83-189555 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
These experiments were undertaken to determine the suitability of a flavor-aversion-conditioning paradigm for detecting the effects of trimethyltin and triethyltin. Both organotins produced flavor aversions whose magnitude depended jointly on the dosage administered and the number of flavor-organotin pairings. Estimated ED 50s (for triethyltin, 1.8 mg/kg; for trimethyltin, 3.1 mg/kg) were smaller than the dosages reported to affect other classes of behavior, but nevertheless represented a substantial percentage (25-45%) of the respective published LD-50 values. Flavor-aversion conditioning may represent a valuable tool for studying the effects of organic and inorganic heavy metals. |
| Supplementary Notes |
Pub. in Neurobehavioral Toxicology and Teratology, v4 n225-230 1982. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Studies on the Flavor Aversions Induced by Trialkyltin Compounds. |
| PUB Date Free Form |
1982 |
| Category Codes |
6T; 57Y |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
320323379 |
| Origin |
NTIS |
| Type |
CAT |
