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Main Title Studies on the Percutaneous Absorption of Parathion and Paraoxon, III. Rate of Absorption of Parathion.
Author Fredriksson., Torsten ;
CORP Author Communicable Disease Center, Atlanta, Ga.
Year Published 1961
Stock Number PB-280 570; PB-280 565
Additional Subjects Absorption(Biology) ; Pesticides ; Insecticides ; Skin(Anatomy) ; Measurement ; Humans ; Laboratory animals ; In vivo analysis ; Experimental data ; Cats ; Insecticides ; Tables(Data) ; Labeled substances ; Cholinesterase inhibitors ; Physiology ; Phosphorus organic compounds ; Reprints ; Parathion ; Phosphoric acid/(diethyl-ester)-(nitrophenyl-ester) ; Bioaccumulation ; Environmental health ; Toxic substances
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NTIS  PB-280 570 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 10p
Abstract The rate of percutaneous absorption of parathion has been estimated in vivo by following the disappearance from a topical deposit of 32P-labelled material in the cat. There was a definite tendency towards inhibition of plasma cholinesterase activity in two cats, while a third animal failed to show this. The amount of radioactivity in the blood five hours after the application corresponded to 0.02 to 0.04 micrograms parathion per ml. It was concluded that parathion is very slowly absorbed, which makes this compound very unsuitable as a model substance in studies of the process of percutaneous absorption. The results have been discussed with special regard to experimental errors involved and to practical implications.
Notes Included in PB-280 565,Journal articles on toxicology. Group 12.
Supplementary Notes Pub. in Acta Dermato-Venereologica, v41 p353-362 1961.
Availability Notes Included in the report, Journal Articles on Toxicology, Group 12, PB-280 565.
Alternate Title Journal articles on toxicology. Group 12.
Title Annotations Reprint: Studies on the Percutaneous Absorption of Parathion and Paraoxon, III. Rate of Absorption of Parathion,
PUB Date Free Form 31 May 61
Category Codes 6T; 6P; 57Y; 57S; 68E
NTIS Prices (Order as PB-280 565, MF A01)
Primary Description 500/01
Document Type NT
Cataloging Source NTIS/MT
Control Number 323740387
Origin NTIS
Type CAT