| Main Title |
Study of Intermolecular Complexes of Bis (p-Chlorophenyl) Acetic Acid and Some Biologically Significant Compounds. |
| Author |
Ross, Ralph T. ;
Biros., Francis J. ;
|
| CORP Author |
Environmental Protection Agency, Perrine, Fla. Primate and Pesticides Effects Lab. |
| Year Published |
1973 |
| Stock Number |
PB-274 733 |
| Additional Subjects |
Chlorine organic compounds ;
Pesticides ;
Nuclear magnetic resonance ;
Molecular relaxation ;
Toxicity ;
DDT ;
Insecticides ;
Reprints ;
Acetic acid/bis(chlorophenyl) ;
Chemical shifts(Nuclear magnetic resonance)
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-274 733 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
10p |
| Abstract |
The results of this investigation have shown that with the use of high resolution NMR relaxation measurement studies, some insight into the importance of molecular binding of p,p'-DDA with BSA and HSA may be obtained. The binding phenomena may be interpreted in terms of preferential stabilization of the aromatic rings by binding sites on the BSA and HSA molecules. This was demonstrated by the greater relaxation rates found for the aromatic protons of the p,p'-DDA than those of the alpha-methine proton. These relaxation rates were quite pD dependent as would be expected from a specific binding mechanism. The binding of p,p'-DDA.BSA and p,p'-DDA.HSA is hydrophobic in nature since a direct relationship was found with ionic strength and relaxation times. The relaxation rates of both complexes increase with decrease in temperature. |
| Supplementary Notes |
Pub. in Mass Spectrometry and NMR Spectroscopy in Pesticide Chemistry, n.d. |
| Availability Notes |
Included in the report, Journal Articles on Pesticide Chemistry, PB-274 732. |
| Title Annotations |
Reprint: A Study of Intermolecular Complexes of Bis (p-Chlorophenyl) Acetic Acid and Some Biologically Significant Compounds, |
| PUB Date Free Form |
1973 |
| Category Codes |
7D; 6F; 99F; 57P |
| NTIS Prices |
(Order as PB-274 732, MF A01) |
| Primary Description |
500/01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
323728418 |
| Origin |
NTIS |
| Type |
CAT |
