| Main Title |
Route of Absorption of DDVP after Oral Administration to Rats. |
| Author |
Laws, Jr., Edward R. ;
|
| CORP Author |
Communicable Disease Center, Atlanta, Ga. |
| Year Published |
1965 |
| Stock Number |
PB-278 091 |
| Additional Subjects |
Absorption(Biology) ;
Pesticides ;
Toxicology ;
Insecticides ;
Ingestion(Biology) ;
Rats ;
Chlorine organic compounds ;
Experimental data ;
Tables(Data) ;
Laboratory animals ;
Blood chemical analysis ;
Metabolism ;
Liver ;
Detoxification ;
Bioassay ;
Reprints ;
DDVP insecticide ;
Toxic substances
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-278 091 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
4p |
| Abstract |
Ten rats were infused by stomach tube with radioactive DDVP while timed samples of portal blood, systemic venous blood, and chyle were taken. Levels of DDVP were determined in all samples and were found to be much higher in portal blood than in either systemic blood or chyle. They were slightly higher in systemic blood than in chyle. It is felt that these findings support the hypothesis that, in the rat, DDVP taken orally is absorbed primarily if not exclusively by the hepatic portal venous system, and, therefore, is routed through the detoxification processes of the liver before reaching the systemic circulation. |
| Supplementary Notes |
Toxicology and Applied Pharmacology, v8 n2 p193-196, Mar 66. |
| Availability Notes |
Included in the report, Journal Articles on Toxicology. Group 3, PB-278 081. |
| Title Annotations |
Reprint: Route of Absorption of DDVP after Oral Administration to Rats, |
| PUB Date Free Form |
8 Feb 65 |
| Category Codes |
6T; 57Y; 68E; 68G |
| NTIS Prices |
(Order as PB-278 081, MF A01) |
| Primary Description |
500/01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
323735838 |
| Origin |
NTIS |
| Type |
CAT |
