| Main Title |
Alterations in Liver Microsomal Metabolism of Parathion Caused by Chronic Administration of Dilantin, Chloroquine. |
| Author |
Davis, J. E. ;
Cranmer, M. F. ;
Peoples., A. ;
|
| CORP Author |
Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab. |
| Year Published |
1971 |
| Stock Number |
PB-277 603 |
| Additional Subjects |
Pesticides ;
Drugs ;
Toxicology ;
Monkeys ;
Rats ;
Metabolism ;
Liver ;
Ribosomes ;
Ingestion(Biology) ;
Toxicity ;
Quinolines ;
Bioassay ;
Quinoline/chloro-(((diethylamino)-methylbutyl)amino) ;
Dilantin ;
Chloroguine
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-277 603 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
1p |
| Abstract |
Monkeys and rats were fed dilantin, chloroquine, or DDE in order to assess the effects of these compounds on liver microsomal metabolism of parathion and the inductive mechanisms involved. The feeding of dilantin and chloroquine affected neither the cytochrome P-450 level in, nor the parathion metabolism by, rat liver microsomes. DDE administratiion greatly increased the liver microsomal metabolism of parathion but had no effect on the cytochrome P-450 level. |
| Supplementary Notes |
Pub. in Toxicology and Applied Pharmacology 19(2) p399-400, Jun 71. |
| Availability Notes |
Included in the report, Journal Articles on Toxicology. Group 1, PB-277 586. |
| Title Annotations |
Reprint: Alterations in Liver Microsomal Metabolism of Parathion Caused by Chronic Administration of Dilantin, Chloroquine, |
| PUB Date Free Form |
1971 |
| Category Codes |
6T; 6F; 6O; 57Y; 68E; 57Q |
| NTIS Prices |
(Order as PB-277 586, MF A01) |
| Primary Description |
600/01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
323734410 |
| Origin |
NTIS |
| Type |
CAT |
