| Main Title |
Reactions, Processes Oxidants and Antioxidant Defense Systems / [electronic resource] : |
| Type |
EBOOK |
| Author |
Grune, Tilman.
|
| Publisher |
Springer Berlin Heidelberg, |
| Year Published |
2005 |
| Call Number |
GE1-350 |
| ISBN |
9783540319160 |
| Subjects |
Environmental sciences ;
Toxicology ;
Medicine, Industrial ;
Ecology ;
Environmental toxicology
|
| Internet Access |
|
| Collation |
XVI, 240 p. online resource. |
| Notes |
Due to license restrictions, this resource is available to EPA employees and authorized contractors only |
| Contents Notes |
Hans Nohl, Andrey Kozlov, Lars Gille, and Katrin Staniek: Endogenous oxidant-generating systems -- Peter Schroeder and Jean Krutmann: Environmental oxidative stress -- Helen Griffith: Chemical modifications of Biomolecules by oxidants -- Kelvin J.A. Davies: Broad spectrum of cellular reactions to oxidative stress -- Tilman Grune, Peter Schroeder, and Hans K. Biesalski: Low-molecular weight antioxidants -- Juan Sastre, Federico Pallardo, and Jose Vina: The glutathione system -- Grzegorz Bartosz: Superoxide dismutases and catalase -- Bente Riis, Henrik Poulsen: DNA-repair mechanisms -- Diana Poppek and Tilman Grune: Protein repair and degradation -- L.-O. Klotz: Metabolic regulation and gene expression in response to oxidative stress -- Enrique Cadenas and Alberto Boveris: Mitochondrial free radical production, antioxidant defenses and cell signaling. Oxidative stress is one of the major symptoms accompanying physiological functions and numerous diseases. Oxidants and free radicals are connected with diseases such as cancer, diabetes, infectious, cardiovascular and neurodegenerative diseases and also in the aging process itself. Therefore, comprehensive knowledge of the underlying mechanisms of oxidant and free radical production and the defence against this permanent threat to cells is important for the understanding of many physiological and pathophysiological processes. This book overviews the basic mechanisms of oxidant formation and antioxidant defences. In addition, the formation of oxidants and their detoxification, the damage of macromolecules and the major repair and removal systems will be highlighted. |
| Place Published |
Berlin, Heidelberg |
| Corporate Au Added Ent |
SpringerLink (Online service) |
| Title Ser Add Ent |
The Handbook of Environmental Chemistry, 2O |
| Alternate Title |
With contribution by numerous experts |
| Host Item Entry |
Springer eBooks |
| PUB Date Free Form |
2005 |
| Series Title Untraced |
The Handbook of Environmental Chemistry, 2O |
| BIB Level |
m |
| Medium |
computer |
| Content |
text |
| Carrier |
online resource |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20140911044516 |
| Language |
eng |
| Origin |
SPRINGER |
| Type |
EBOOK |
| OCLC Rec Leader |
03440nam a22005415i 45 |
