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RECORD NUMBER: 2750 OF 2835

Main Title Transactions: Tropospheric Ozone and the Environment. Papers from an International Conference.
Author Berglund, R. L. ; Lawson, D. R. ; McKee, D. J. ;
CORP Author University of Southern California, Los Angeles. School of Medicine.;Health Effects Research Lab., Research Triangle Park, NC. Epidemiology Branch.;California State Air Resources Board, Sacramento.
Publisher 1991
Year Published 1991
Report Number EPA-68-D8-0017 ;ARB-A6-202-33; EPA/600/A-92/164;
Stock Number PB92-217017
Additional Subjects Respiratory diseases ; Air pollution effects(Humans) ; Epidemiology ; Ozone ; Socioeconomic factors ; Pathology ; Smoking ; Bronchitis ; Reprints ; Centriacinar Region disease
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NTIS  PB92-217017 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 22p
Abstract The question 'Does air pollution cause significant adverse effects in humans' misses the real health issue. The more appropriate question is: what role does air pollution play in causing, promoting, facilitating, and/or exacerbating the lung disease that is present in all adults. The present study is a first step in the direction of inventory, an assessment of pathologically overt injury to a key unit of the acinus, the centriacinar region (CAR). The lungs of 107 of 118 youths (14-25 years of age), who died in vehicular accidents or were homicide victims, were suitable for pathologic examination, and the extent and severity of disease was determined. Of the 107 youths, 29 (27%) had severe CAR disease as judged by scores of 5 or more (on a scale of 1-10) for both severity and extent. The high incidence and severity of CAR disease in youths is unprecedented and cannot be attributed to any single agent. The pathogenesis is undoubtedly multifactorial, with socioeconomic factor dominant, in particular a suboptimal level of health care, greater impact of respiratory tract infections, high levels of air pollution, and heavy smoking and some illicit drug use. Air pollution is highly suspect for a substantial contributory role.
Supplementary Notes Sponsored by Health Effects Research Lab., Research Triangle Park, NC. Epidemiology Branch, and California State Air Resources Board, Sacramento.
Title Annotations Reprint: Transactions: Tropospheric Ozone and the Environment. Papers from an International Conference.
Category Codes 68A; 68G; 57U
NTIS Prices PC A03/MF A01
Primary Description 600/10
Document Type NT
Cataloging Source NTIS/MT
Control Number 226927911
Origin NTIS
Type CAT