| Main Title |
Genetic Evaluation of Extracts of Dow Corning MDF-0107 Foley Catheter Dispersion in the Ames Bacterial Assay, with Cover Letter dated 04/20/1994. |
| CORP Author |
Dow Corning Corp., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1994 |
| Report Number |
OTS-86940001349 |
| Stock Number |
OTS0558130 |
| Additional Subjects |
Toxicology ;
Health effects ;
Toxic substances ;
Hexamethyldisiloxane ;
Laboratory animals ;
Genotoxicity ;
Gene mutations ;
Bacteria ;
In vitro ;
CAS No 107-46-0 ;
CAS No 70131-67-8
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0558130 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
17p |
| Abstract |
The test material was evaluated for genetic activity in a microbial assay (Ames, et al., MUTATION RESEARCH 31:347, 1975) with and without the addition of mammalian metabolic activation. Salmonella typhimurium Str. TA-1535, TA-1537, TA-1538, TA-98, and TA-100 were used as indicator organisms. Dimethy1sulfoxide, absolute ethanol, and sterile physiological saline extracts of the test material prepared by continuous rotary shaking (150 rpm/37C/24 hours) in accordance with the U.S.P. Class VI Plastics Method for biological testing of solid materials, were each introduced into the test system at concentrations of extract ranging from 50 to 3.12pl. A Spot Plate Test against each of the indicator organisms was conducted using the extracts directly on the surface of the agar test plates. No evidence of genetic activity was observed. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
28 Apr 1994 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A03/MF A03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
010500800 |
| Origin |
NTIS |
| Type |
CAT |
