| Main Title |
Prenatal Effects of Herbicides: Evaluation by the Prenatal Development Index. |
| Author |
Courtney., K. Diane ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, N.C. Experimental Biology Div. |
| Year Published |
1976 |
| Report Number |
EPA/600/J-77/124; |
| Stock Number |
PB-284 753 |
| Additional Subjects |
Herbicides ;
Pesticides ;
Toxicology ;
Prenatal care ;
Cleft palate ;
Mice ;
Laboratory animals ;
Experimental data ;
Chlorine organic compounds ;
Congenital abnormalities ;
Mortality ;
Body weight ;
Evaluation ;
Responses ;
Indexes(Ratios) ;
Tables(Data) ;
Ingestion(Biology) ;
Reprints ;
Teratogenesis ;
Toxic substances ;
D 2-4 herbicide ;
Acetic acid/trichlorophenoxy ;
T 2-4-5 herbicide ;
Orange defoliant
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-284 753 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
15p |
| Abstract |
The herbicides 2,4-D and 2,4,5-T and many of the esters of these compounds produced cleft palates in CD-1 mice. Silvex and Agent Orange also produced cleft palates. Depending on the dose and means of administration variable responses relating to the production of cleft palates, effect on fetal weight, and effect on fetal mortality were obtained. In order to view these data comprehensibly, the Prenatal Development Index was determined. This index was computed from the incidence of malformed fetuses, fetal mortality and fetal body weight. This made it possible to evaluate data from some experiments with feto-toxic doses of compounds in which the high incidence of fetal mortality and consequently low incidence of viable fetuses obscured the response. |
| Supplementary Notes |
Pub. in Archives of Environmental Contamination and Toxocology, v6 n33 p33-46 1977. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Prenatal Effects of Herbicides: Evaluation by the Prenatal Development Index. |
| PUB Date Free Form |
31 Jan 76 |
| Category Codes |
6T; 6F; 57Y; 68E |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
323746149 |
| Origin |
NTIS |
| Type |
CAT |
