| Main Title |
Protein adduct forming chemicals for exposure monitoring : chemicals selected for further study / |
| Author |
Schnell, Frank C. ;
Chiang, T. C.
|
| Other Authors |
|
| CORP Author |
Lockheed Engineering and Sciences Co., Inc., Las Vegas, NV.;Environmental Monitoring Systems Lab., Las Vegas, NV. |
| Publisher |
U.S. Environmental Protection Agency, Environmental Monitoring Systems Laboratory ; Available from the National Technical Information Service, |
| Year Published |
1989 |
| Report Number |
EPA/600/4-89/035; 68-03-3249; EPC-68-03-3249 |
| Stock Number |
PB90-151762 |
| OCLC Number |
36679277 |
| Subjects |
Chemicals--Testing ;
Toxicity testing--United States
|
| Additional Subjects |
Proteins ;
Carcinogens ;
Toxicity ;
Hydrolysis ;
Tables(Data) ;
In vitro analysis ;
In vivo analysis ;
Hemoglobins ;
Aromatic compounds ;
Detoxification ;
Diagrams ;
Adducts ;
Metabolic activation ;
Dose-response relationships ;
Environmental monitoring ;
Environmental exposure pathways
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EJED |
EPA/600/4-89/035 |
|
OCSPP Chemical Library/Washington,DC |
01/13/2001 |
| ELBD |
EPA 600-4-89-035 |
|
AWBERC Library/Cincinnati,OH |
05/08/1998 |
| NTIS |
PB90-151762 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
vii, 169 p. : ill. ; 28 cm. |
| Abstract |
The present report is an in-depth characterization of twenty-two chemicals and the protein (primarily hemoglobin) adducts that are formed following exposure to these compounds. These chemicals were recommended for further study in a recent internal report which described the state of the science with regard to chemicals and adducts potentially of interest for exposure monitoring. The twenty-two compounds which are evaluated are ranked and placed in one of the following categories: (1) Simple alkylating and arylating agents that form N-terminal valine adducts, (2) Aromatic amines that form hydrolyzable cysteine adducts, (3) Chemicals that form hydrolyzable, but less well-characterized adducts, (4) Chemicals that form characterized, but nonhydrolyzable adducts, and (5) Chemicals that form poorly characterized adducts. |
| Notes |
"October 1989." "EPA/600/4-89/035." "Contract no. 68-03-3249." "Work assignment manager, Charles H. Nauman." Includes bibliographical references. |
| Place Published |
Las Vegas, Nev. Springfield, Va. |
| Supplementary Notes |
Sponsored by Environmental Monitoring Systems Lab., Las Vegas, NV. |
| Corporate Au Added Ent |
Lockheed Engineering & Sciences Company.; Environmental Monitoring Systems Laboratory (Las Vegas, Nev.); United States. Environmental Protection Agency. Office of Research and Development. |
| PUB Date Free Form |
1989. |
| NTIS Prices |
PC A09/MF A01 |
| BIB Level |
m |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20010111154226 |
| Language |
eng |
| Origin |
OCLC |
| Type |
MERGE |
| OCLC Rec Leader |
01468nam 2200361Ka 45010 |
