| Main Title |
The Chemokine System in Experimental and Clinical Hematology [electronic resource] / |
| Type |
EBOOK |
| Author |
Bruserud, Oystein.
|
| Publisher |
Springer Berlin Heidelberg : Imprint: Springer, |
| Year Published |
2010 |
| Call Number |
RC261-271 |
| ISBN |
9783642126390 |
| Subjects |
Medicine ;
Oncology ;
Hematology
|
| Internet Access |
|
| Collation |
XII, 208 p. online resource. |
| Notes |
Due to license restrictions, this resource is available to EPA employees and authorized contractors only |
| Contents Notes |
The Chemokine System in Experimental and Clinical Hematology -- Chemokine Decoy Receptors: Structure-Function and Biological Properties -- Role of Chemokines in the Biology of Natural Killer Cells -- Chemokines in Angiogenesis -- Genetic Polymorphisms in the Cytokine and Chemokine System: Their Possible Importance in Allogeneic Stem Cell Transplantation -- The Chemokine System: A Possible Therapeutic Target in Acute Graft Versus Host Disease -- Homing in on Acute Graft vs. Host Disease: Tissue-Specific T Regulatory and Th17 Cells -- The Chemokine Network in Acute Myelogenous Leukemia: Molecular Mechanisms Involved in Leukemogenesis and Therapeutic Implications -- CXCR4 in Clinical Hematology -- Immunobiology of Heparin-Induced Thrombocytopenia. The aim of the issue is to describe and explain the importance of the chemokine system in hematology. As described in the introduction the chemokine system is probably important for many aspects of normal as well as malignant hematopoiesis. A major focus is the development and treatment of hematologic malignancies, including the immunobiology of stem cell transplantation." The present reviews illustrate that chemokines can be involved in leukemogenesis. The chemokine system is also important both for the crosstalk between malignant cells and their neighbouring nonmalignant stromal cells (including endothelial cells) as well as for immunoregulation in patients treated with allogeneic stem cell transplantation. Thus, chemokines are important both for the pathogenesis and treatment of hematological diseases. |
| Place Published |
Berlin, Heidelberg |
| Corporate Au Added Ent |
SpringerLink (Online service) |
| Title Ser Add Ent |
Current Topics in Microbiology and Immunology, 341 |
| Host Item Entry |
Springer eBooks |
| PUB Date Free Form |
2010 |
| Series Title Untraced |
Current Topics in Microbiology and Immunology, 341 |
| BIB Level |
m |
| Medium |
computer |
| Content |
text |
| Carrier |
online resource |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20131219113026 |
| Language |
eng |
| Origin |
SPRINGER |
| Type |
EBOOK |
| OCLC Rec Leader |
03123nam a22004575i 45 |
