| Main Title |
Inhibition of Gap-Junctional Intercellular Communication between Chinese Hamster Lung Fibroblasts by Di (2-Ethylhexyl) Phthalate (DEHP) and Trisodium Nitrilotriacetate Monohydrate (NTA). |
| Author |
Malcolm, A. R. ;
Mills., L. J. ;
|
| CORP Author |
Environmental Research Lab., Narragansett, RI. ;Science Applications International Corp., Narragansett, RI. |
| Publisher |
c1989 |
| Year Published |
1989 |
| Report Number |
EPA/600/J-89/179 ;ERLN-795; |
| Stock Number |
PB90-140336 |
| Additional Subjects |
Lung ;
Toxicology ;
Carcinogens ;
Inhibitors ;
Reprints ;
Intercellular junctions ;
Di(2-ethylhexyl)phthalate ;
Ethylhexyl ;
Trisodium nitrilotriacetate monohydrate ;
Chinese hamsters ;
Fibroblasts
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB90-140336 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
11p |
| Abstract |
Di(2-ethylhexyl)phthalate and trisodium nitrilotriacetate monohydrate, two apparently nongenotoxic carcinogens, were tested for effects on gap-junctional communication between Chinese hamster V79 lung fibroblasts. Both compounds inhibited gap-junctional communication in a concentration-dependent manner. The inhibiting effects of these chemicals on gap-junctional communication in vitro correlate with their tumor-promoting activity. Such results further support the hypothesis that inhibition of gap-junctional communication is an in vitro biomarker for some tumor-promoting chemicals. (Copyright (c) 1989 Princeton Scientific Publishing Co.) |
| Supplementary Notes |
Pub. in Cell Biology and Toxicology, v5 n2 p145-153 1989. Prepared in cooperation with Science Applications International Corp., Narragansett, RI. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Inhibition of Gap-Junctional Intercellular Communication between Chinese Hamster Lung Fibroblasts by Di (2-Ethylhexyl) Phthalate (DEHP) and Trisodium Nitrilotriacetate Monohydrate (NTA). |
| Category Codes |
57Y; 57I |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/05 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
005319979 |
| Origin |
NTIS |
| Type |
CAT |
