| Main Title |
Summary of Mortality Rates and Necropsy Observations of Tissue Masses and Nodules with Cover Sheet Dated 07/17/1989 (Sanitized). |
| CORP Author |
Hazleton Labs., Falls Church, VA.; Rohm and Haas Co., Philadelphia, PA.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
2000 |
| Report Number |
86-890001399S |
| Stock Number |
OTS0521016 |
| Additional Subjects |
Toxicology ;
Health effects ;
Methyl Methacrylate (80-62-6) ;
Chronic Toxicity ;
Mammals ;
Hamsters ;
Inhalation ;
Toxic substances ;
Laboratory animals ;
CAS No 80-62-6
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0521016 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
5p |
| Abstract |
Chronic toxicity was evaluated in hamsters exposed to methyl methacrylate vapor at concentrations of 0, 25, 100, or 400 ppm for a period of 18 months. Mortality rates, after 64 weeks of treatment, in the control, low-, mid-, and high-dose groups were 12.5, 22.2, 16.1, and 28.6% (males) and 32.7, 33.9, 32.1 and 54.5% (females), respectively. The incidence of tissue masses or nodules noted at necropsy of animals found dead or moribund, in the control, low-, mid-, and high-dose groups, were 2/7, 1/12, 1/9, and 2/16 (males) and 2/18, 0/19, 1/18 and 3/30 (females) respectively. Results on statistical tests of these results were notreported. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with Rohm and Haas Co., Philadelphia, PA. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
2000 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A01/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028802390 |
| Origin |
NTIS |
| Type |
CAT |
