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RECORD NUMBER: 154 OF 172

Main Title Sister Chromatid Exchanges in Mammalian Meiotic Chromosomes.
Author Allen, J. W. ; Walters, C. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1984
Report Number EPA/600/D-84/241;
Stock Number PB85-108694
Additional Subjects Chromosomes ; Mammals ; Hamsters ; Sister chromatid exchanges ; Meiosis ; Cricetulus migratorium
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB85-108694 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 31p
Abstract Very little is known about sister chromatid exchanges (SCEs) in meiotic cells--only that they occur (1) and reveal frequency and distribution patterns apparently unaffected by cross-over (CO) exchange conditions in those cells; (2) unfortunately, the number of studies from which to draw these general conclusions is small due to a variety of methodological difficulties. Only a few organisms have been analyzed for baseline SCEs in meiotic tissue. No information pertaining to the extent or significance of SCE induction by mutagens during meiosis is available. In the present work, an Armenian hamster (Cricetulus migratorius) spermatocyte system is described in terms of its methodological features and its applications for baseline SCE analyses. This system appears to have considerable promise for comparative studies of mechanisms involved in SCE and CO, and for development as an assay to detect and determine the significance of induced SCEs in meiotic cells.
PUB Date Free Form Sep 84
Category Codes 6C; 57F
NTIS Prices PC A03/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 501823850
Origin NTIS
Type CAT