| Main Title |
Placental Transfer and Fetal Deposition of Hexachlorobenzene in the Hamster and Guinea Pig. |
| Author |
Courtney, K. D. ;
Andrews, J. E. ;
Grady, M. A. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;Northrop Services, Inc., Research Triangle Park, NC. |
| Year Published |
1985 |
| Report Number |
EPA/600/J-85/144; |
| Stock Number |
PB86-101805 |
| Additional Subjects |
Toxicology ;
Hamsters ;
Guinea pigs ;
Dosage ;
Reprints ;
Benzene/hexachloro ;
Hexachlorobenzene
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB86-101805 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
12p |
| Abstract |
Hexachlorobenzene (HCB) was administered at dose levels of 0, 1.0, 10.0, or 50.0 mg HCB/kg body wt by gavage to pregnant hamsters and guinea pigs for 6 days up to the time of liver development in the fetus. Samples of maternal fat, thymus, skin, liver, lung, brain, spleen, urinary bladder, muscle, plasma, and blood were analyzed for HCB concentration. Additionally, fetuses, placentas, and yolk sacs were analyzed for HCB content. HCB was found in all tissues assayed. The highest concentrations of HCB were found in the hamster tissues, with the hamster fetuses having a fivefold greater concentration of HCB than the guinea pig fetuses. Comparisons were made of the hamster and guinea pig data with similar data in the mouse and rat. |
| Supplementary Notes |
Prepared in cooperation with Northrop Services, Inc., Research Triangle Park, NC. |
| Availability Notes |
Pub. in Environmental Research 37, p239-249 1985. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Placental Transfer and Fetal Deposition of Hexachlorobenzene in the Hamster and Guinea Pig. |
| PUB Date Free Form |
c1985 |
| Category Codes |
6T; 57Y |
| NTIS Prices |
Not available NTIS |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
535324834 |
| Origin |
NTIS |
| Type |
CAT |
