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RECORD NUMBER: 104 OF 172

Main Title Investigation of Possible Age Effects on Meiotic Chromosomal Recombination and Segregation in Armenian Hamster Spermatocytes.
Author Allen, J. W. ; Gwaltney, C. W. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1985
Report Number EPA/600/J-85/346;
Stock Number PB86-175411
Additional Subjects Meiosis ; Aging(Biology) ; Spermatocytes ; Hamsters ; Chromosomes ; Reprints ;
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NTIS  PB86-175411 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 9p
Abstract Male Armenian hamsters (Cricetulus migratorius; 2N:22) were evaluated for age effects upon meiotic recombination and aneuploidy incidence. Primary spermatocytes from young and old animals revealed similar chiasma frequencies. The incidence of terminal-type chiasmata in sex bivalents was also measured and determined to be unaffected by age. Percentages of univalents and of hyperploid metaphase II cells were evaluated by chromosome groups, based upon individual chromosome morphologies. Regardless of age, the larger dichiasmate chromosomes were seldom observed as univalents, or as extra chromosomes in hyperploid cells. The monochiasmate small autosomes and sex chromosomes were noted with frequencies approximating 5.5 - 6.5% in animals from both age groups. However, only the small autosomes appeared to be significantly implicated in hyperploidy. Although still a rare event, metaphase II hyperploidy was significantly increased in older animals (0.9% incidence in young; 2.4% in old).
Supplementary Notes Pub. in Cytobios 43, n172/173 p225-232 Dec 85.
NTIS Title Notes Journal article.
Title Annotations Reprint: Investigation of Possible Age Effects on Meiotic Chromosomal Recombination and Segregation in Armenian Hamster Spermatocytes.
PUB Date Free Form 1985
Category Codes 6C; 57F
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 614222689
Origin NTIS
Type CAT