||Initial Submission: Acute Oral Toxicity and Skin Absorption and Irritation of 3-Chloropropionitrile in Rats and Guinea Pigs with Cover Letter dated 08/26/1992.
||Eastman Kodak Co., Rochester, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Health effects ;
Acute toxicity ;
Primary dermal irritation ;
Guinea pigs ;
CAS No 542-76-7
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||The report pertains to 3-chloropropanenitrile (synonym: 3-chloropropionitrile) (CAS No. 542-76-7) and is being submitted because of lethality with central nervous system (CNS) signs observed in an acute oral toxicity study in rats. The oral LD50 is 10-50 mg/kg in rats. The material is also a slight skin irritant. The dermal LD50 is 0.05-0.1 cc/kg in guinea pigs. The report is being identified as a study involving other than human effects (Unit II.B.2.b of CAP Agreement).
||The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
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|PUB Date Free Form
||26 Aug 1992
||57Y; 57U; 68G; 99; 44G
||PC A01/MF A01