| Main Title |
Effects of Exposure to Ozone on Susceptibility to Experimental Tuberculosis. |
| Author |
Thomas, Gail ;
Fenter, James ;
Ehrlich, R. ;
Gardner, D. E. ;
|
| CORP Author |
IIT Research Inst., Chicago, IL. Life Sciences Research Div.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1981 |
| Report Number |
EPA-68-02-1273; EPA-600/J-81-645; |
| Stock Number |
PB83-243311 |
| Additional Subjects |
Ozone ;
Toxicology ;
Mice ;
Laboratory animals ;
Bacteria ;
Lung ;
Guinea pigs ;
Response ;
Reprints ;
Mycobacterium tuberculosis ;
Hypersensitivity ;
Air pollution effects(Animals)
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB83-243311 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
10p |
| Abstract |
Exposure of mice to 1.96 mg/cu. m. ozone (03) 3 h/day, 5 days/week, for up to 8 weeks beginning at 1 or 2 weeks after challenge with Mycobacterium tuberculosis R1Rv resulted in significant enhancement of bacterial titers in the lungs at 5 through 8 weeks after challenge when compared to mice compared to controls. Exposure of guinea pigs to 2.9 mg/cu. m 03 for 3 h immediately after challenge with M. tuberculosis resulted in a suppression of the cutaneous delayed hypersensitivity response, without affecting the serum hemagglutination antibody titers. However, exposure of guinea pigs to 0.98 mg/cu. m 03 3h/day for 5 days, initiated within 3 h after the infectious challenge, enhanced hemagglutination antibody titers initially, but the delayed hypersensitivity reaction did not differ from controls. |
| Availability Notes |
Pub. in Toxicology Letters, v9 p11-17 1981. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Effects of Exposure to Ozone on Susceptibility to Experimental Tuberculosis. |
| PUB Date Free Form |
c1981 |
| Category Codes |
6T; 6F; 57Y; 68A |
| NTIS Prices |
Not available NTIS |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
331551770 |
| Origin |
NTIS |
| Type |
CAT |
