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Main Title Summary of Range Finding Report on 2-Ethyl Hexoic Acid with Cover Letter.
CORP Author Union Carbide Corp., Oak Ridge, TN. Office of Health, Safety, and Environmental Affairs.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1984
Report Number 878214663
Stock Number OTS-0206613
Additional Subjects Health effects ; Toxicity ; Acute ; Mammals ; Rats ; Guinea pigs ; Rabbits ; Laboratory animals ; Oral ; Dermal ; 2-ethylhaxanocoid acid ; CAS No 149-57-5 ; Primary eye irritation ; Primary dermal irritation ; Union Carbide Corporation
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NTIS  OTS-0206613 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 18p
Abstract Single doses by mouth to male albino rats resulted in an approximate LD50 of 3.0 gm./kg. This places 2-ethyl hexoic acid in Grade 3 of our oral toxicity rating system along with sorbic and lactic acids. The LD(sub 50) by skin absorption for guinea pigs in the 4 day contact period is 6.3 gm./kg. Slight dryness and cracking of the skin occurs with 10 gm./kg. after a 24 hour contact period. The undiluted material is in Grade 5 of our eye burn rating system as 0.001 ml. produces corneal necrosis of the rabbit eye. Undiluted and 100 dilutions in acetone cause etythema of the skin of rabbit bellies. The eye hazard is obvious and based on the above findings any prolonged contact with the skin should be avoided. No saturated vapor exposures were made because of the low vapor pressure which obviates any vapor hazard when the material is not heated.
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PUB Date Free Form 7 Aug 1984
Category Codes 57Y
NTIS Prices PC A03/MF A03
Document Type NT
Cataloging Source NTIS/MT
Control Number 019001760
Origin NTIS
Type CAT