| Main Title |
1,2-butylene Oxide: Skin Sensitization Potential in the Guinea Pig with Cover Letter from Bowman Cm, 2020 dow Center to Timm G, Ots dated 01/23/1984. |
| CORP Author |
Dow Chemical Co., Midland, MI. Toxicology Research Lab.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1984 |
| Report Number |
40-8475031 |
| Stock Number |
OTS0507304 |
| Additional Subjects |
Toxicology ;
Health effects ;
Butylene Oxide ;
Primary Dermal Sensitization ;
Mammals ;
Guinea Pigs ;
Dermal ;
Toxic substances ;
Laboratory animals ;
CAS No 106-88-7
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0507304 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
Skin sensitization potential of 1,2- butylene oxide was evaluated in 10 male Hartley albino guinea pigs exposed to 0.1 ml of undiluted test compound 4 times over a 7 day period, followed 2 weeks later by a single challenge exposure. Treatment did not produce signs of sensitization in any of the guinea pigs, whereas 9 of 10 guinea pigs exposed to a positive control solution (0.1 ml of DER 331) exhibited a positive response indicative of sensitization. The authors concluded that the test compound was not a potential human skin sensitizer. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1984 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A02/MF A02 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028801180 |
| Origin |
NTIS |
| Type |
CAT |
