Full Record Display for the EPA National Library Catalog
RECORD NUMBER: 34 OF 41| Main Title | Pulmonary Antioxidants. | |||||||||||
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| Author | Massaro, E. J. ; Grose, E. C. ; Hatch, G. E. ; Slade, R. ; | |||||||||||
| CORP Author | Health Effects Research Lab., Research Triangle Park, NC. | |||||||||||
| Year Published | 1987 | |||||||||||
| Report Number | EPA/600/D-87/143; | |||||||||||
| Stock Number | PB87-188132 | |||||||||||
| Additional Subjects | Antioxidants ; Lung ; Air pollution ; Tissues(Biology) ; Toxicity ; Defense systems ; Glutathione ; Tocopherol ; Ascorbic acid ; Uric acid ; Enzymes ; Defense mechanisms ; Air pollution effects(Humans) ; Air pollution effects(Animals) | |||||||||||
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| Collation | 52p | |||||||||||
| Abstract | One of the most vital of the cellular defenses against pollution is an 'antioxidant armanentarium' which consists of oxidant scavenging molecules such as vitamin E, glutathione, vitamin C, and uric acid as well as a number of enzymes (superoxide dismutase, semidehydroascorbate reductase, catalase, GSH synthetase, GSH peroxidase, GSH reductase, and GSH transferase) and appears to function in keeping oxidant forces under control. Pollutants can upset the oxidant/antioxidant balance of cells by inhibiting vital enzymes, by reacting with oxidant scavengers, or by forming free radical intermediates which initiate uncontrolled tissue reactions with molecular oxygen. The book chapter reviews possible interactions between pollutants and the oxidant/antioxidant balance. | |||||||||||
| PUB Date Free Form | May 87 | |||||||||||
| Category Codes | 68A; 68G; 57Y; 57O | |||||||||||
| NTIS Prices | PC A04/MF A01 | |||||||||||
| Primary Description | 600/11 | |||||||||||
| Document Type | NT | |||||||||||
| Cataloging Source | NTIS/MT | |||||||||||
| Control Number | 720522413 | |||||||||||
| Origin | NTIS | |||||||||||
| Type | CAT |