| Main Title |
Acute Operant Behavior Study of Inhaled Commercial Hexane in the Albino Rat. Draft with Attachments and Cover Letter dated 12/27/89. |
| CORP Author |
Bio-Research Laboratories, Redmond, WA. ;American Petroleum Inst., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
5 Jan 1990 |
| Year Published |
1990 |
| Report Number |
FYI-OTS-0190-0733; |
| Stock Number |
OTS-0000733 |
| Additional Subjects |
Hexane ;
Inhalation ;
Rats ;
Body weight ;
Food intake ;
Albino rats
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0000733 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
156p |
| Abstract |
Four groups of 6 male and 6 female Sprague-Dawley rats, maintained on a fixed interval schedule by food reinforcement, were treated by nose-only inhalation for 6 hours with commercial hexane (hexane) at mean (S.D.), concentrations of 0, 873 (36.4), 2974 (39.6) or 9187 (171.8) ppm. The vapor generated was found to contain 15.8 to 16.6% methylcyclopentane and 51.6 to 52.5% n-hexane. The control group was treated similarly in all respects except it received air only. The animal response on the fixed interval 60 second schedule was tested in a 30 minute session immediately after exposure and on post-exposure days 1 and 2. No animals died or were sacrificed due to treatment. There were no toxicologically significant clinical findings attributed to treatment with hexane. The body weights and food intakes of the hexane treatment rats were unaffected by treatment. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
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| Category Codes |
57 |
| NTIS Prices |
PC A09/MF A02 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
019103570 |
| Origin |
NTIS |
| Type |
CAT |
