| Main Title |
Metabolism and pharmacology of fluorine-containing compounds / |
| Author |
Lee, Cheng Chun,
|
| Publisher |
Aerospace Medical Research Laboratories, Aerospace Medical Division, Air Force Systems Command, United States Air Force, |
| Year Published |
1966 |
| Report Number |
AMRL TR 66-110 |
| OCLC Number |
17552670 |
| Subjects |
Fluorine--Toxicology ;
Fluorides--Metabolism ;
Fluorides--Physiological effect ;
Fluorine--Compounds
|
| Local Library Info |
| Library |
Local Subject |
Local Note |
| EJE |
Cas no. 7782-41-4 |
|
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EJEM |
QD181.F1L4 1966 |
|
OCSPP Chemical Library/Washington,DC |
01/06/1995 |
|
| Collation |
viii, 73 pages : illustrations ; 28 cm. |
| Notes |
Includes bibliographic references (pages 72-73). Research supported by the Aerospace Medical Division, Air Force Systems Command, United States Air Force; report prepared by Midwest Research Institute, Kansas City, Missouri, under contract no. Contract Number: AF 33(615)-2472 |
| Contents Notes |
Acute inhalation, intraperitoneal and/or oral toxicities of AMOX and TAMA were determined in rats and mice. IP absorption was studied in rats. AMOX produced strong irritation resulting in pulmonary edema and hemorrhage after inhalation; and local denatured changes and accumulation of clear exudate after intraperitoneal injection. TAMA was less toxic on the weight basis. Both AMOX and TAMA were quickly absorbed after IP injection. Fluoride increased quickly in the blood and concentrated in various tissues especially in the thyroid, bone and teeth. Most of the administered fluoride was excreted in the urine and a considerable amount was also recovered in the feces. |
| Place Published |
Wright-Patterson Air Force Base, Ohio, |
| Corporate Au Added Ent |
Aerospace Medical Research Laboratories (U.S.) ; Aerospace Medical Research Laboratories (U.S.) |
| PUB Date Free Form |
1966. |
| BIB Level |
m |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
19950105101357 |
| Language |
ENG |
| Origin |
OCLC |
| Type |
CAT |
| OCLC Rec Leader |
00716nam 2200229K 45020 |
