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Main Title Studies on the Flavor Aversions Induced by Trialkyltin Compounds.
Author MacPhail, R. C. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1982
Report Number EPA-600/J-82-301;
Stock Number PB83-189555
Additional Subjects Toxicology ; Rats ; Laboratory animals ; Reprints ; Heavy metals ; Trimethyltin ; Triethylin ; Flavor aversions
Library Call Number Additional Info Location Last
NTIS  PB83-189555 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 8p
Abstract These experiments were undertaken to determine the suitability of a flavor-aversion-conditioning paradigm for detecting the effects of trimethyltin and triethyltin. Both organotins produced flavor aversions whose magnitude depended jointly on the dosage administered and the number of flavor-organotin pairings. Estimated ED 50s (for triethyltin, 1.8 mg/kg; for trimethyltin, 3.1 mg/kg) were smaller than the dosages reported to affect other classes of behavior, but nevertheless represented a substantial percentage (25-45%) of the respective published LD-50 values. Flavor-aversion conditioning may represent a valuable tool for studying the effects of organic and inorganic heavy metals.
Supplementary Notes Pub. in Neurobehavioral Toxicology and Teratology, v4 n225-230 1982.
NTIS Title Notes Journal article.
Title Annotations Reprint: Studies on the Flavor Aversions Induced by Trialkyltin Compounds.
PUB Date Free Form 1982
Category Codes 6T; 57Y
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 320323379
Origin NTIS
Type CAT