| Main Title |
Toxicological Assessment of Biodegraded Pentachlorophenol: Microtox (Trade Name) and Fish Embryos. |
| Author |
Middaugh, D. P. ;
Resnick, S. M. ;
Lantz, S. E. ;
Heard, C. S. ;
Mueller, J. G. ;
|
| CORP Author |
Environmental Research Lab., Gulf Breeze, FL. ;Technical Resources, Inc., Gulf Breeze, FL. ;SBP Technologies, Inc., Gulf Breeze, FL. |
| Publisher |
c1993 |
| Year Published |
1993 |
| Report Number |
EPA/600/J-93/058 ;CONTRIB-777; |
| Stock Number |
PB93-168920 |
| Additional Subjects |
Pesticides ;
Toxicology ;
Fishes ;
Non-mammalian embryo ;
Biodeterioration ;
Pseudomonas ;
Teratogenic compounds ;
Water pollution effects(Animals) ;
Reprints ;
Phenol/pentachloro ;
Menidia beryllina
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB93-168920 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
A Gram-negative bacterium, Pseudomonas sp. strain SR3, was isolated from soil at a former wood treatment plant in north central Florida. The ability of this bacterium to degrade pentachlorophenol (PCP) was confirmed by growing cells in a basal salts medium in which PCP was the only source of carbon and energy. Degradation from a measured concentration of PCP was observed within 120 h of incubation in the presence of PCP-induced cells of Pseudomonas sp. strain SR3. Microtox 5 min EC50 toxicity tests revealed that aqueous solutions of PCP, measured concentrations 39-40 microgram/ml were toxic but that final biodegraded samples, 0.0006 microgram PCP/ml were nontoxic. However, bioassays with embryonic inland silversides, Menidia beryllina, showed that the biodegraded samples were embryotoxic or teratogenic. Results indicate that while biodegradation of PCP was nearly complete, intermediate metabolites of the degradation process or undergraded impurities in PCP were toxic or teratogenic. |
| Supplementary Notes |
See also PB92-129733. Prepared in cooperation with Technical Resources, Inc., Gulf Breeze, FL., and SBP Technologies, Inc., Gulf Breeze, FL. |
| Availability Notes |
Pub. in Archives of Environmental Contamination and Toxicology 24, p165-172 1993. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Toxicological Assessment of Biodegraded Pentachlorophenol: Microtox (Trade Name) and Fish Embryos. |
| Category Codes |
68E; 68D; 57Y; 57K |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/04 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
314124275 |
| Origin |
NTIS |
| Type |
CAT |
