| Main Title |
Initial Submission: Additional Cross-over Reproduction Studies with Fenarimol in Wistar and Sprague-dawley Rats with Cover Letter dated 08/17/92. |
| CORP Author |
Lilly (Eli) and Co., Indianapolis, IN.; Dow Corning Corp., Hemlock, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1992 |
| Report Number |
88-920005153 |
| Stock Number |
OTS0544127 |
| Additional Subjects |
Toxicology ;
Health effects ;
Fenarimol ;
Reproduction/fertility Effects ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Toxic substances ;
Laboratory animals ;
CAS No 60168-88-9
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0544127 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
Fenarimol (CAS No. 60168-88-9) was evaluated for reproductive toxicity. The test material was administered in an oral gavage dose of 35 mg/kg to Wistar and Sprague Dawley male and female rats (number of rats in groups were not specified) for 28 days prior to mating and for 7 days during the mating period. The females were dosed through postpartum day 20. For each strain of rats the groups consisted of: untreated males mated with untreated females; untreated males mated with treated females; and treated males mated with untreated females. In both strains fertility was reduced when males were treated, and treatment of the females was associated with evidence of dystocia and impairment of the parturition process resulting in a reduction both in liveborn litter size and in early and postpartum survival of the progeny. This summary was briefly summarized. No further information was reported. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with Dow Corning Corp., Hemlock, MI. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1992 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A02/MF A02 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028803580 |
| Origin |
NTIS |
| Type |
CAT |
