| Main Title |
Initial Submission: a Range-finding Teratology Study in Albino Rabbits with Cga-71818 Technical (Final Report) with Attachments and Cover Letter Dated 01/07/1992. |
| CORP Author |
Wil Res Labs; CIBA-GEIGY Corp., Toms River, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1992 |
| Report Number |
88-920000626 |
| Stock Number |
OTS0535183 |
| Additional Subjects |
Toxicology ;
Health effects ;
1-(2-(2 ;
4-dichloro phenyl)-n-pentyl) -1h-1 ;
2 ;
4-triazole ;
Reproduction/fertility Effects ;
Teratogenicity ;
Mammals ;
Rabbits ;
Oral ;
Gavage ;
Toxic substances ;
Laboratory animals ;
CAS No 66246-88-6
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0535183 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
100p |
| Abstract |
Penconazole (66246-88-6) was evaluated for developmental toxicity. Five pregnant New Zealand White rabbits per group were dosed with 0, 50, 100, 250, 500, or 1000 mg/kg/day by oral gavage on days 7-20 of gestation. All does at 500 and 1000 mg/kg/day died or were sacrificed moribund. Reduced body weight and food consumption were observed at 250 mg/kg/day. Increased resorptions, decreased number of live fetuses and decreased fetal weights were observed at 250 mg/kg/day. No external fetal malformations were observed. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with CIBA-GEIGY Corp., Toms River, NJ. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1992 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A06/MF A06 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028803310 |
| Origin |
NTIS |
| Type |
CAT |
