| Main Title |
Female Fertility Study of Sprague-dawley Rats Exposed by Inhalation Route to Acetone Cyanohydrin with Cover Letter dated 04/25/1986. |
| CORP Author |
Monsanto Environmental Sciences Center, St. Louis, MO.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1986 |
| Report Number |
878216398 |
| Stock Number |
OTS0510326 |
| Additional Subjects |
Toxicology ;
Health effects ;
Acetone Cyanohydrin (75-86-5) ;
Reproduction/fertility Effects ;
Mammals ;
Rats ;
Inhalation ;
Toxic substances ;
Laboratory animals ;
CAS No 75-86-5
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0510326 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
89p |
| Abstract |
Fertility was evaluated in groups of female Sprague-Dawley rats (24/group) receiving whole body exposure to acetone cyanohydrin at nominal concentrations of 10, 30 or 60ppm in a dynamic air flow chamber, 6hrs/day, 7days/week for 21 days. On day 21, females were mated to untreated males and exposure was continued until copulation was confirmed. Females were sacrificed at mid-gestation (gestation days 13-15). There was no effect of treatment for all animals as indicated by mortality, body weights and necropsy observations. Female fertility parameter values were comparable between treatment groups and the control group for: mating efficiency, pregnancy rates, number of live implants and pre- and postimplantation losses. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1986 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A06/MF A06 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028801450 |
| Origin |
NTIS |
| Type |
CAT |
