| Main Title |
Support: Letter from Dow Chemical Co. to USEPA regarding 1,3-Dimethyl-2-Imidazolidone with Attachments dated 10/18/1996. |
| CORP Author |
Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1996 |
| Report Number |
8EHQ-1096-13621 |
| Stock Number |
OTS0558495-1 |
| Additional Subjects |
Toxicology ;
Health effects ;
Toxic substances ;
1 ;
3-dimethyl-2-imidazolidinone ;
Reproduction ;
Fertility effects ;
Teratogenicity ;
Mammals ;
Rats ;
Dermal ;
CAS No 80-73-9
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0558495-1 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
6p |
| Abstract |
Preliminary, unaudited results from a dermal teratology study (in which the material was administered for 6 hours/day on gestation days 6 to 15 at 0, 10, 100, and 400 mg/kg/day) indicate a statistically significant decrease in gravid uterine weight and fetal body weight at the 400 mg/kg/day dose level. These parameters were not affected at the 100 or 10 mg/kg/day dose groups. Maternal body weights were significantly decreased at 400 mg/kg/day during gestation days 16-21. Body weight gains of the female rats given 400 mg/kg/day were also statistically decreased on days 6-9, 9-12, 12-16, 0-21 and 6-16. At 100 mg/kg/day, body weight gains were statistically lower than the controls during the treatment period (.days 6-16) and days 19-21 of gestation. No effects on maternal body weights or body weight gains were observed at 10 mg/kg/day. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
22 Oct 1996 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A02/MF A02 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
010501230 |
| Origin |
NTIS |
| Type |
CAT |
