| Main Title |
Methyl Methacrylate Monomer Teratogenicity in the Rabbit with Attachments and Cover Sheet Dated 07/17/1989 (Sanitized). |
| CORP Author |
Imperial Chemical Industries Ltd., London (England).; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
2000 |
| Report Number |
86-890001392S |
| Stock Number |
OTS0521015 |
| Additional Subjects |
Toxicology ;
Health effects ;
Methyl Methacrylate (80-62-6) ;
Reproduction/fertility Effects ;
Teratogenicity ;
Mammals ;
Rabbits ;
Parenteral ;
Intraperitoneal ;
Toxic substances ;
Laboratory animals ;
CAS No 80-62-6
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0521015 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
10p |
| Abstract |
Developmental toxicity was evaluated in groups of 12 female Dutch rabbits injected intraperitoneally with methyl methacrylate at dose levels of 0, 0.004, 0.04, or 0.4 ml/kg bw/day, on gestation days 6-18, followed by fetal examination on gestation day 29. The maternal mortality rate was 25% in all treated groups, probably from complications related to the injection. At the high-dose level, the compound was embryotoxic (increased early resorptions) and fetotoxic (reduced fetal weight and skeletal ossification), but was not teratogenic. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
2000 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A02/MF A02 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028802380 |
| Origin |
NTIS |
| Type |
CAT |
