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RECORD NUMBER: 651 OF 780

Main Title Short-Term Carcinogenesis and Mutagenesis Bioassays of Unregulated Automotive Emissions.
Author Huisingh, J. L. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1981
Report Number EPA-600/J-82-056;
Stock Number PB84-101815
Additional Subjects Bioassay ; Exhaust gases ; Toxicology ; Risk ; Reprints ; Carcinogenesis ; Mutagenesis ; Automobile exhaust ; Health risks ; Environmental health
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Library Call Number Additional Info Location Last
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NTIS  PB84-101815 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 14p
Abstract Evaluation of the potential risk of a chemical or environmental emission causing chronic health effects requires data from one or more of the following sources: epidemiologic and clinical studies of human exposure and effects; chronic (long term) bioassays in animals; and short-term bioassays in animals, animal and human cells, insects, plants, and microorganisms. Although it is advantageous to have data from as many different sources and bioassays systems as possible, human and chronic animal data are essential to the definitive determination of whether a substance poses a carcinogenic hazard to humans. Often, however, such data are not available for the evaluation of emissions from new or alternative technologies. In particular, data from long-term human or animal studies are rarely available before the introduction of new emission sources. Short-term tests, therefore, provide important suggestive evidence of a substance's potential to cause genotoxic effects.
Supplementary Notes Pub. in Bulletin of the New York Academy of Medicine, Second Series, v57 n4 p251-261 May 81.
NTIS Title Notes Journal article.
Title Annotations Reprint: Short-Term Carcinogenesis and Mutagenesis Bioassays of Unregulated Automotive Emissions.
PUB Date Free Form 1981
Category Codes 6T; 6F; 57Y; 68G; 68A
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 400621662
Origin NTIS
Type CAT