Main Title |
Short-Term Carcinogenesis and Mutagenesis Bioassays of Unregulated Automotive Emissions. |
Author |
Huisingh, J. L. ;
|
CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1981 |
Report Number |
EPA-600/J-82-056; |
Stock Number |
PB84-101815 |
Additional Subjects |
Bioassay ;
Exhaust gases ;
Toxicology ;
Risk ;
Reprints ;
Carcinogenesis ;
Mutagenesis ;
Automobile exhaust ;
Health risks ;
Environmental health
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB84-101815 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
14p |
Abstract |
Evaluation of the potential risk of a chemical or environmental emission causing chronic health effects requires data from one or more of the following sources: epidemiologic and clinical studies of human exposure and effects; chronic (long term) bioassays in animals; and short-term bioassays in animals, animal and human cells, insects, plants, and microorganisms. Although it is advantageous to have data from as many different sources and bioassays systems as possible, human and chronic animal data are essential to the definitive determination of whether a substance poses a carcinogenic hazard to humans. Often, however, such data are not available for the evaluation of emissions from new or alternative technologies. In particular, data from long-term human or animal studies are rarely available before the introduction of new emission sources. Short-term tests, therefore, provide important suggestive evidence of a substance's potential to cause genotoxic effects. |
Supplementary Notes |
Pub. in Bulletin of the New York Academy of Medicine, Second Series, v57 n4 p251-261 May 81. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Short-Term Carcinogenesis and Mutagenesis Bioassays of Unregulated Automotive Emissions. |
PUB Date Free Form |
1981 |
Category Codes |
6T; 6F; 57Y; 68G; 68A |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
400621662 |
Origin |
NTIS |
Type |
CAT |