| Main Title |
Delayed Reproductive Effects Following Exposure to Toxic Chemicals during Critical Developmental Periods. |
| Author |
Gray, L. E. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
1989 |
| Year Published |
1989 |
| Report Number |
EPA/600/D-89/150; |
| Stock Number |
PB90-112830 |
| Additional Subjects |
Reproduction(Biology) ;
Morphology ;
Pathology ;
Androgens ;
Estrogens ;
Progestational hormones ;
Rodents ;
Humans ;
Males ;
Females ;
Toxic substances ;
Prenatal exposure delayed effects ;
Diethylstilbestrol
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB90-112830 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
56p |
| Abstract |
The studies presented in the review indicate that perinatal exposure of the fetal or neonatal rodent to a toxicant can adversely affect reproductive development, reduce fertility and accelerate reproductive senescence. In rodents and humans exposure to DES, estrogens, androgens and progestins during critical developmental periods produce morphological and pathological alterations of the reproductive tract of males and females. DES treatment causes cancer, infertility and serious morphological abnormalities of the reproductive tract in all species examined. |
| Category Codes |
57Y; 68G |
| NTIS Prices |
PC A04/MF A01 |
| Primary Description |
600/10 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
935219978 |
| Origin |
NTIS |
| Type |
CAT |
