| Main Title |
Occupational Pesticide Exposure and Renal Tubular Dysfunction. |
| Author |
Mann, Joel B. ;
Davies, John E. ;
Shane., Robald W. ;
|
| CORP Author |
National Communicable Disease Center, Atlanta, Ga. |
| Year Published |
1967 |
| Stock Number |
PB-278 096 |
| Additional Subjects |
Toxicology ;
Pesticides ;
Insecticides ;
Industrial medicine ;
Kidney ;
Physiology ;
Phosphorus organic compounds ;
Cholinesterase ;
Enzymes ;
Nitrophenols ;
Humans ;
Exposure ;
Toxic substances ;
Occupational safety and health ;
Parathion ;
Metabolites ;
Urinalysis ;
Reprints
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-278 096 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
An apparent etiologic relationship between occupational exposure to pesticides and renal tubular malfunction was discovered incidentally during the development of a practical surveillance technique for persons occupationally exposed to parathion, an organophosphate type of insecticide. For this surveillance method, grab samples of urine were obtained and analyzed for paranitrophenol, the major urinary metabolite of parathion. Urinary levels of paranitrophenol, expressed in parts per million (ppm), were then independently correlated with observed spray technique and with measurements of red cell cholinesterase. An average urinary level of approximately 4.5 ppm was found to be the level above which red cell cholinesterase became increasingly depressed and which was associated with a 70 per cent absenteeism rate due to pesticide-induced illness. (Portions of this document are not fully legible) |
| Supplementary Notes |
Pub. in Acute Glomerulonephritis, Proceedings, Annual Conference in the Kidney (17th), p219-226 1967. |
| Availability Notes |
Included in the report, Journal Articles on Toxicology. Group 2, PB-278 094. |
| Title Annotations |
Reprint: Occupational Pesticide Exposure and Renal Tubular Dysfunction, |
| PUB Date Free Form |
1967 |
| Category Codes |
6T; 6J; 57Y; 68G; 68E; 57U |
| NTIS Prices |
(Order as PB-278 094, MF A01) |
| Primary Description |
500/01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
323735883 |
| Origin |
NTIS |
| Type |
CAT |
