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OLS Field Name OLS Field Data
Main Title Mechanisms of Aldehyde-Induced Bronchial Reactivity: Role of Airway Epithelium.
Author Leikauf, G. D. ;
CORP Author Cincinnati Univ. Medical Center, OH.;Health Effects Inst., Cambridge, MA.
Publisher c1991
Year Published 1991
Report Number HEI/RR-92/49;
Stock Number PB93-179927
Additional Subjects Bronchi ; Air pollution effects(Animals) ; Aldehydes ; Eicosanoids ; Toxicology ; Guinea pigs ; Epithelium ; Leukotrienes ; Prostaglandins ; Acrolein ; Formaldehyde ; Mitogens ;
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB93-179927 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 08/23/1993
Collation 56p
Abstract The purpose of the study was to determine whether exposures to environmentally relevant concentrations of two aldehydes of low molecular weight were associated with impaired airway function. Specifically, the study addressed questions of the relative irritant potency of formaldehyde and acrolein on the induction of increased bronchial reactivity to acetylcholine in guinea pigs. The relationship of bronchial reactivity to epithelial damage and inflammation were also examined after both in vivo and in vitro exposures.
Supplementary Notes Sponsored by Health Effects Inst., Cambridge, MA.
NTIS Title Notes Research rept. Jul 86-Jan 91.
Category Codes 68A; 57Y; 57B
NTIS Prices PC A04/MF A01
Document Type NT
Cataloging Source NTIS/MT
Control Number 316133457
Origin NTIS
Type CAT