| Main Title |
Barium Bioavailability as the Chloride, Sulfate, or Carbonate Salt in the Rat. |
| Author |
McCauley, P. T. ;
Washington, I. S. ;
|
| CORP Author |
Health Effects Research Lab., Cincinnati, OH. |
| Year Published |
1983 |
| Report Number |
EPA-600/J-83-048; |
| Stock Number |
PB84-101799 |
| Additional Subjects |
Barium ;
Toxicology ;
Rats ;
Laboratory animals ;
Concentration(Composition) ;
Diets ;
Ingestion(Biology) ;
Biological availability ;
Drinking water
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB84-101799 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
11p |
| Abstract |
This study was conducted to determine how the bioavailability of a low concentration of barium (Ba) in drinking water is affected by anion speciation. Male Sprague Dawley rats weighing 250-300 grams were maintained on a diet of less than 1 mg Ba/kg of food for at least 1 month prior to experimentation. Rats were given 10.0 mg Ba131/liter as sulfate (SO4), chloride (C1), or carbonate (CO3) at pH 7.0. Animals were sacrificed at 2, 5, 10, 20, 30, 60, and 120 minutes and 24 hours after intubation. When 131Ba was administered, as C1, 131Ba in blood rose linearly for 10 minutes and then less rapidly until the highest number of counts was measured at 60 minutes. At 24 hours 131Ba was still at 90% of peak levels. In eye, 131Ba increased linearly for 1 hour. |
| Supplementary Notes |
Pub. in Drug and Chemical Toxicology, v6 n2 p209-217 1983. |
| NTIS Title Notes |
Journal article. |
| PUB Date Free Form |
1983 |
| Category Codes |
6T; 57Y |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
400621644 |
| Origin |
NTIS |
| Type |
CAT |
