| Main Title |
Evaluating the human health effects of hazardous wastes : reproduction and development, neurotoxicity, genetic toxicity and cancer / |
| Author |
Dyer, Robert S. ;
Houk, V. S. ;
Reiter, L. W.
|
| Other Authors |
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
U.S. Environmental Protection Agency, Health Effects Research Laboratory, |
| Year Published |
1991 |
| Report Number |
EPA/600/D-91/236 |
| Stock Number |
PB92-110352 |
| Subjects |
Hazardous wastes
|
| Additional Subjects |
Health hazards ;
Reproduction(Biology) ;
Carcinogens ;
Mutagens ;
Nervous system ;
Toxicity ;
Test methods ;
Salmonella typhimurium ;
DNA damage ;
Motor activity ;
Mutagenicity tests ;
Bioassay ;
Dose-response relationships ;
Humans ;
Teratogens ;
Hazardous wastes
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB92-110352 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
20 pages ; 28 cm |
| Abstract |
Several approaches are available for characterizing potential toxicity of wastes. The paper describes biological tests which are appropriate for identifying waste as neurotoxic, genotoxic, or likely to produce developmental or reproductive effects. The tests recommended are, for neurotoxicity a functional observational battery, coupled with a measure of motor (bodily movement) activity; for genetic toxicity, the 'Ames' test of mutagenicity in Salmonella and a test of clastogenicity (DNA damage); and for developmental and reproductive toxicity, the Chernoff-Kavlock assay and a multigenerational reproductive assay. In addition, the paper identifies several generic factors which must be considered in performing any evaluations of hazardous wastes. |
| Notes |
Cover title. "EPA 600/D-91/236." Includes bibliographical references. Microfiche. |
| Contents Notes |
EPA/600/D-91/236. |
| Place Published |
{Research Triangle Park, NC} : |
| Corporate Au Added Ent |
United States. Environmental Protection Agency. Office of Air and Radiation. |
| PUB Date Free Form |
1991. |
| NTIS Prices |
PC A03/MF A01 |
| BIB Level |
m |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20010131140218 |
| Language |
eng |
| Origin |
NTIS |
| Type |
MERGE |
| OCLC Rec Leader |
01203nam 2200301Ka 45020 |
