| Main Title |
Initial Submission: Letter to USEPA re: Results of Two-Week Preliminary Oral Toxicity Study with S-1955 (Confidential Information), an Experiment Insecticide and Miticide, in Dogs, dated 11/09/99 (Sanitized). |
| CORP Author |
;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
12 Nov 1999 |
| Year Published |
1999 |
| Report Number |
8EHQ-1199-14589S; |
| Stock Number |
OTS-0559836 |
| Additional Subjects |
Insecticides ;
Miticides ;
Toxicity ;
Oral toxicity ;
Dogs ;
Laboratory animals ;
Dosage ;
Convulsions ;
Mortality ;
S-1955
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0559836 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
6p |
| Abstract |
The company has recently completed a two week preliminary oral toxicity study with dogs. S-1955 (experimental insecticide and miticide) was administered daily by oral capsule to beagle dogs (two/sex/group) at doses of 0 (control), 10, 30, and 100 mg/kg/day for two weeks. Two males and one female in the highest dose group showed signs of convulsions. One female and one male died on day 14. In addition, tremor, salivation and/or hypoactivity were observed in other animals receiving this dose level. For those animals receiving 30 mg/kg/day, slight decreases in food consumption were observed, but no neurotoxic signs were observed. Histopathological examinations have not yet been performed on the animals. |
| Supplementary Notes |
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| Availability Notes |
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| Category Codes |
57Y; 57P |
| NTIS Prices |
PC A02/MF$25.00 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
019101980 |
| Origin |
NTIS |
| Type |
CAT |
