| Main Title |
Initial Submission: Letter from Eastman Kodak to USEPA re: Acute/Subacute Oral and Derm Tox Tests with Disubstituted Morpholinyl-2-Cyclopenb-1-One, with Attachments and dated 11/16/99 (Sanitized). |
| CORP Author |
Eastman Kodak Co., Rochester, NY.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
18 Nov 1999 |
| Year Published |
1999 |
| Report Number |
8EHQ-1199-14594S; |
| Stock Number |
OTS-0559841 |
| Additional Subjects |
Toxicity ;
Concentration ;
Oral dosage ;
Mortality ;
Topical exposure ;
Rats ;
Laboratory animals ;
Dermal irritation ;
Disubstituted morpholinyl-2-cyclopen-1-one ;
Acute oral toxicity ;
Eastman Kodak
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0559841 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
39p |
| Abstract |
An acute toxicity screening study was conducted by administering single oral doses of 2000, 1000, 600, 300, or 100 mg of test substance per kg of body weight by gavage to fasted rats (2 females/dose level). Approximately four hours after administration of these doses to the fasted animals, the rats were fed and allowed ad libitum access to feed for the remainder of the study. Subsequently, each female at the 1000, 600, 300, and 100 mg/kg dose levels received a daily dose identical to the initial dose for three consecutive days to provide a preliminary assessment of subacute toxicity. To assess the potential of the test substance to cause dermal irritation, one of the two rats assigned to the 100 mg/kg dose group was additionally exposed to 0.5 gram of the test substance topically for a period of four hours. |
| Supplementary Notes |
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| Availability Notes |
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| Category Codes |
57Y |
| NTIS Prices |
PC A04/MF$25.00 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
019102000 |
| Origin |
NTIS |
| Type |
CAT |
