Full Record Display for the EPA National Library Catalog

RECORD NUMBER: 363 OF 1115

Main Title Effects of low level carbon monoxide exposure : blood lipids and coagulation parameters /
Author Brinkhous, K. M. ; Brinkhouse., K. M.
CORP Author North Carolina Univ., Chapel Hill. Dept. of Pathology.;Health Effects Research Lab., Research Triangle Park, N.C.
Publisher U.S. Environmental Protection Agency, Health Effects Research Laboratory,
Year Published 1977
Report Number EPA/600/1-77/032; EPA-68-02-1281
Stock Number PB-269 340
OCLC Number 42838161
Subjects Carbon monoxide--Physiological effect
Additional Subjects Carbon monoxide ; Toxicity ; Blood coagulation ; Lipids ; Dosage ; Exercise(Physiology) ; Fibrin ; Blood ; Concentration(Composition) ; Males ; Experimental data ; Exposure ; Physiological effects ; Cholesterol ; Glycerides ; Hematocrit ; Platelets ; Prothrombin ; Thromboplastin ; Thrombin ; Cigarette smoking ; Carbonylhemoglobin ; Air pollution effects(Humans) ; Blood coagulation factor VIII ; Environmental health
Internet Access
Description Access URL
https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=91013E7D.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJBD  EPA 600-1-77-032 c.1 Headquarters Library/Washington,DC 05/27/2014
EJED  EPA 600/1-77/032 OCSPP Chemical Library/Washington,DC 07/01/2005
EKBD  EPA-600/1-77-032 Research Triangle Park Library/RTP, NC 06/06/2003
ELBD ARCHIVE EPA 600-1-77-032 Received from HQ AWBERC Library/Cincinnati,OH 10/04/2023
ELBD  EPA 600-1-77-032 AWBERC Library/Cincinnati,OH 09/02/2016
NTIS  PB-269 340 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation iv, 23 pages ; 28 cm.
Abstract The study examined the effects of carbon monoxide (CO) in 50 and 100 ppm doses on response to treadmill exercise, blood coagulation and blood lipids in normal men. Twenty-three men were exposed to CO or to air in a double-blind protocol. After exposure, each underwent a graded exercise treadmill test which was terminated at 85% maximal heart rate. Blood for measurement of carboxyhemoglobin (COHb), hematocrit, platelet count, prothrombin time, partial thromboplastin time, thrombin time, fibrin split products, factor VIII, platelet aggregation, serum cholesterol and triglycerides was drawn at baseline, preexercise and postexercise. COHb did not change on air days but reached a mean of 2.17% on 50 ppm days and 4.15% on 100 ppm days. The mean duration of exercise was 19 sec shorter on CO days than on air days (f = 4.93). The greatest effect was on 100 ppm days (f = 8.00). Coagulation parameters and cholesterol and triglyceride measurements were not significantly affected by CO exposure.
Notes "EPA-600/1-77-032." EPA contract no. 68-02-1281; EPA project officer: Edward D. Haak, Jr.
Place Published Research Triangle Park, NC
Access Notes Also available via the World Wide Web.
Corporate Au Added Ent Health Effects Research Laboratory (Research Triangle Park, N.C.); United States. Environmental Protection Agency. Office of Research and Development.; University of North Carolina (System). Department of Pathology.
Title Ser Add Ent Research reporting series. Environmental health effects research ; EPA 600/1-77/032.
PUB Date Free Form June 1977
Series Title Untraced Environmental health effects research series ; EPA 600/1-77/032
Category Codes 6T; 6F; 13B; 57Y; 68G; 68A
NTIS Prices PC A03/MF A01
Primary Description 600/11
BIB Level m
Medium unmediated
Content text
Carrier volume
Cataloging Source OCLC/T
Control Number 323720648
OCLC Time Stamp 20160826062720
Language eng
Origin OCLC
Type MERGE
OCLC Rec Leader 01895cam 2200445Ka 45010