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RECORD NUMBER: 163 OF 1115

Main Title Cardiovascular Effects of o,p'-DDD.
Author Cueto, Jr., Cipriano ;
CORP Author Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab.
Year Published 1970
Stock Number PB-277 613
Additional Subjects Pesticides ; Epinephrine ; Norepinephrine ; Insecticides ; Cardiovascular system ; Toxicology ; Dogs ; Laboratory animals ; Experimental data ; Dosage ; Responses ; Histamines ; Blood pressure ; Blood plasma ; Histology ; Bioassay ; Reprints ; DDD insecticide ; Glucocorticoids ; Toxic substances
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NTIS  PB-277 613 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 2p
Abstract Daily oral administation of o,p'-DDD to dogs produced glucocorticoid deficiency. Blood pressure and heart contractile force and rate response to graded doses of epinephrine and norepinephrine were determined in treated and untreated dogs. Vasopressor and cardioaccelerator responses to ouabain were similar in treated and untreated dogs. The induced glucocorticoid deficiency produced little apparent direct circulatory effect but diminished the ability to withstand stressful procedures such as thoracotomy and multiple injections of vasopressor amines.
Supplementary Notes Pub. in Industrial Medicine, v39 n1 p55-56, Jan 70.
Availability Notes Included in the report, Journal Articles on Toxicology. Group 1, PB-277 586.
Title Annotations Reprint: Cardiovascular Effects of o,p'-DDD,
PUB Date Free Form 1970
Category Codes 6T; 6F; 57Y; 68E
NTIS Prices (Order as PB-277 586, MF A01)
Primary Description 500/01
Document Type NT
Cataloging Source NTIS/MT
Control Number 323734517
Origin NTIS
Type CAT