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Main Title

Health Assessment Document for 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) and Related Compounds. Volume 1 of 3.

CORP Author

Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.

Publisher

Aug 94

Year Published

1994

Report Number

EPA/600/BP-92/001A ;OHEA-I-486-V1;

Stock Number

PB94-205465

Additional Subjects

Tetrachlorodibenzodioxin ; Health hazards ; Risk assessment ; Toxicity ; Dioxins ; Public health ; Biological effects ; Health effects ; Exposure ; Tolerances(Physiology) ; Dose-response relationships ; Epidemiology ; Pharmacokinetics ; Immunology ; Nervous system ; Immune system ; Reproduction(Physiology) ; Fetal development ; Growth adnormalities ; Carcinogenicity

Internet Access

Description	Access URL
	https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=2000B661.PDF

Holdings

Library	Call Number	Additional Info	Location	Last Modified	Checkout Status
NTIS	PB94-205465	Some EPA libraries have a fiche copy filed under the call number shown.		07/26/2022

Collation

428p

Abstract

The U.S. Environmental Protection Agency has undertaken the task of preparing a scientific reassessment of the health risks of exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and chemically similar compounds collectively known as dioxin. Significant advances have occurred in the scientific understanding of mechanisms of dioxin toxicity, of the carcinogenic and other adverse health effects of dioxin in people, of the pathways to human exposure, and of the toxic effects of dioxin to the environment. The health assessment document consists of three volumes. Volume 1 describes the disposition and pharmacokinetics; mechanism(s) of action; acute, subchronic, and chronic toxicity; immunotoxicity; developmental and reproductive toxicity; and carcinogenicity of TCDD in animals.

Supplementary Notes