| Main Title |
Comparative Analysis of the Electrostatic Potentials of Dibenzofuran and Some Dibenzo-p-dioxins. |
| Author |
Murray, J. S. ;
Zilles, B. A. ;
Jayasuriya, K. ;
Politzer, P. ;
|
| CORP Author |
New Orleans Univ., LA. Dept. of Chemistry.;Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
c1986 |
| Year Published |
1986 |
| Report Number |
EPA/600/J-86/514; |
| Stock Number |
PB90-117144 |
| Additional Subjects |
Electrostatics ;
Furans ;
Graphs(Charts) ;
Toxicity ;
Measurement ;
Reprints ;
Dioxin/tetrachloro-dibenzo ;
Biological effects
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB90-117144 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
6p |
| Abstract |
Electrostatic potential maps of dibenzofuran, dibenzo-p-dioxin, 2,8-dichloro-3,7-dimethyldibenzo-p-dioxin, 2,3,7,8-tetrafluorodibenzo-p-dioxin, and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) are presented and compared. The biological activities of the molecules increase from zero for the first two to very strong for the highly toxic TCDD. The analysis of the electrostatic potentials suggests certain key features that may be necessary for the effective interaction of the classes of compounds with a cytosolic receptor, which is believed to be the initial step leading to various toxic responses and other biological activity. (Copyright (c) 1986 American Chemical Society.) |
| Supplementary Notes |
Pub. in Jnl. of the American Chemical Society, v108 p915-918 1986. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Comparative Analysis of the Electrostatic Potentials of Dibenzofuran and Some Dibenzo-p-dioxins. |
| Category Codes |
99F; 57Y; 68E |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/10 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
936217246 |
| Origin |
NTIS |
| Type |
CAT |
