| Main Title |
Twenty-eight Day Dermal Toxicity Study of API 83-15 in the Rabbit (Final Draft Report) with Cover Letter dated 02/12/86. |
| CORP Author |
American Petroleum Inst., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
Jan 1986 |
| Year Published |
1986 |
| Report Number |
FYI-AX-0286-0431; |
| Stock Number |
OTS-0000431-3 |
| Additional Subjects |
Rabbits ;
Chemicals ;
Environmental health ;
Public health ;
Animal experiments ;
Dermal toxicity ;
API 83-12 ;
Light alkylate naptha
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0000431-3 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
806p |
| Abstract |
The test article, API 83-15, was applied to the shaved intact skin of New Zealand White rabbits three times a week for a total of 12 applications over a 28-day period. The test article was applied at dose levels of 200 (Group 2), 1000 (Group 3), and 2000 (Group 4) mg/kg to groups of five male and five female rabbits. In addition, five male and five female rabbits served as sham-treated negative controls. All animals were observed twice daily for toxic and pharmacologic signs; dermal irritation was scored daily (according to the Draize System (a)). Body weights were measured and recorded for each rabbit at the end of the quarantine period, at weekly intervals during the study, and prior to termination. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| Category Codes |
57U; 68 |
| NTIS Prices |
PC A99/MF$25.00 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
010001830 |
| Origin |
NTIS |
| Type |
CAT |
