| Main Title |
Acute Inhalation Toxicity Evaluation of a Petroleum-Derived Hydrocarbon (Compound API No. 83-06) in Rats, Final Report with Cover Letter dated 10/30/1984. |
| CORP Author |
American Petroleum Inst., Washington, DC.; Litton Bionetics, Inc., Rockville, MD.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1984 |
| Report Number |
FYI-AX-1184-0359-IN |
| Stock Number |
OTS0000359 |
| Additional Subjects |
Toxicology ;
Health effects ;
Heavy catalytic reformed naphtha ;
Acute toxicity ;
Naphtha ;
Rats ;
Chemicals ;
Mortality ;
Dermal toxicity ;
CAS No 9072-35-9 ;
CAS No 64741-68-0
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0000359 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
35p |
| Abstract |
A petroleum-derived hydrocarbon mixture, API No. 83-06, was evaluated for its acute inhalation toxicity. Five young adult rats of each sex were exposed to a target vapor concentration of 5.0 milligrams/liter (mg/L) for 4 hours. Vapors were generated by a countercurrent distillation process and administered in the breathing air of the animals utilizing dynamic whole-body exposure methods. During pre-exposure atmosphere characterization tests, API No. 83-06, when generated using the method produced an atmosphere that was entirely of vapors. Analysis of vapor concentrations was performed by continuously measuring total hydrocarbon content and yielded a time weighted average of 5.04 & 0.900 ag/L for API material. No animals died or exhibitea clinical signs during the course of the exposures or during the 14 day observation period. Individual and mean body weights were not affected by exposure to the test material. Histopathological examination of lung tissues yielded minimal to moderate pulmonary findings. The possibility that these could be attributed to the exposure could not be ruled out. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5301 Shawnee Road, Alexandria, VA, 22312, USA. |
| PUB Date Free Form |
1 Nov 1984 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A04/MF A04 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
100701150 |
| Origin |
NTIS |
| Type |
CAT |
