| Main Title |
Initial Submission: Letter from Dupont Chemical to USEPA regarding Embryo-Fetal and Terotogenicity Study of Silane in Rats with Cover Letter and Attachments dated 08/20/1992. |
| CORP Author |
Du Pont de Nemours (E.I.) and Co., Wilmington, DE.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1992 |
| Report Number |
8EHQ-0892-10197 |
| Stock Number |
OTS0570779 |
| Additional Subjects |
Toxicology ;
Health effects ;
Toxic substances ;
Silane(bis(4- fluropheny))(methyl) (1H-1 ;
2 ;
4-triazol) ;
Reproduction ;
Fertility effects ;
Combined teratogenicity ;
Reproductive effects ;
Mammals ;
Rats ;
Oral ;
Gavage ;
CAS No 85509-19-9
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0570779 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
11p |
| Abstract |
Rats were dosed at levels of 0, 10, 50, and 250 mg/kg; maternal toxicity and deaths occurred at 250 mg/kg; a significant increase in the incidence of fetuses with cleft palate and with absence of renal papilla was seen at 250 mg/kg. Embryo-fetal toxicity was noted at all levels tested (decreased fetal weight, increased fetal death at 250 mg/kg; and increase incidence of skeletal variations at 10 mg/kg and above). |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
24 Aug 1992 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A03/MF A03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
010503020 |
| Origin |
NTIS |
| Type |
CAT |
