| Main Title |
Letter from Exxon Co. to USEPA Regarding Enclosed Information on the 12-Week Vapor Exposure Study Concerning Isopar C, Isoparaffinic Hydrocarbon Solvent and Varsol 40 with Attachments. |
| CORP Author |
Exxon Chemical Co., Houston, TX. Technology Div.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
3 Oct 1979 |
| Year Published |
1979 |
| Report Number |
8EHQ-1079-0312; |
| Stock Number |
OTS-0200630 |
| Additional Subjects |
Vapors ;
Solvents ;
Hydrocarbons ;
Toxicity ;
Females ;
Mortality ;
Body weight ;
Hematology ;
Clinical chemistry ;
Mice ;
US EPA ;
Kidney disease ;
Inhalation ;
Exposure ;
Cell membranes ;
Chemicals ;
Evaluation ;
Lesions ;
Isoparaffinic hydrocarbon solvent ;
Exxon Corporation ;
Isopar C ;
Varsol 40
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0200630 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
600p |
| Abstract |
The submission presents a summary of the final results from 12-week inhalation toxicity studies of ISOPAR C and VARSOL 40 solvents in male and female rats. Evidence of kidney damage is reported for male rats exposed to the solvents. Both ISOPAR C and VARSOL 40 appear to produce typical toxic nephrosis (degeneration of the epithelial cells of the kidney tubules without damage to the basement membrane). Mercury, dichromate, uranium, chloroform, carbon tetrachloride, dioxane, and many other chemicals produce similar lesions in the kidney. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
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| Category Codes |
57Y; 57O |
| NTIS Prices |
PC A99/MF A06 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
035501270 |
| Origin |
NTIS |
| Type |
CAT |
