| Main Title |
Generation of Mutagenic Transformation Products during the Irradiation of Simulated Urban Atmospheres. |
| Author |
Kleindienst, T. E. ;
Smith, D. F. ;
Hudgens, E. E. ;
Claxton, L. D. ;
Bufalini, J. J. ;
|
| CORP Author |
NSI Technology Services Corp., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
c1992 |
| Year Published |
1992 |
| Report Number |
EPA/600/J-92/421; |
| Stock Number |
PB93-141208 |
| Additional Subjects |
Air pollution sampling ;
Mutagens ;
Photochemical reactions ;
Urban areas ;
Biological effects ;
Smog ;
Test chambers ;
Irradiation ;
Urban areas ;
Biological effects ;
Volatile organic compounds ;
Bioassay ;
Mutagen screening ;
Nitrogen oxides ;
Microorganisms ;
Hydrocarbons ;
Reprints ;
Chemical reaction mechanisms
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB93-141208 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
12p |
| Abstract |
Mixtures of air pollutants simulating urban atmospheres were irradiated in a smog chamber, and the resultant products were monitored for the production of mutagenic and other hazardous compounds. The production of biologically active compounds was detected through use of the Ames mutagenicity assay with Salmonella typhimurium, strain TA100. Irradiations of the pollutant mixture were conducted at HC/NOx ratios of 20 and 11. Overall, the mutagenicity of the products and the formation of oxygenated primary and secondary reactions products were greater for the simulations with the higher initial HC/NOx value. The origin of the mutagenicity from the reactant mixture was examined by conducting experiments with individual paraffinic, olefinic, and aromatic hydrocarbons. The chemicals examined during this aspect of the study were the paraffin n-butane, the olefin propylene, and the aromatic toluene. For the conditions studied, the activity of the toluene products was generally greater than that of propylene or n-butane, and the propylene products showed greater activity than did the n-butane products. The production of n-butane products was generally limited by its low rate of reaction with hydroxyl radicals. Photooxidation products from secondary reactions were most important in the toluene and propylene systems. (Copyright (c) 1992 American Chemical Society.) |
| Supplementary Notes |
Pub. in Environmental Sciences and Technology, v26 n2 p320-329 May 92. See also PB90-259870, PB89-207161 and PB87-199675. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Generation of Mutagenic Transformation Products during the Irradiation of Simulated Urban Atmospheres. |
| Category Codes |
68A; 99E; 57Y; 91A |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/10 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
307031271 |
| Origin |
NTIS |
| Type |
CAT |
