| Main Title |
Approaches to risk assessment for multiple chemical exposures / |
| Author |
Stara, J. F. ;
Erdreich, Linda S. ;
Erdreich, L. S.
|
| Other Authors |
|
| CORP Author |
United States. Environmental Protection Agency. Environmental Criteria and Assessment Office.; Environmental Protection Agency, Cincinnati, OH. Environmental Criteria and Assessment Office.; Dynamac Corp., Rockville, MD. |
| Publisher |
U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, |
| Year Published |
1984 |
| Report Number |
EPA-600/9-84-008 |
| Stock Number |
PB84-182369 |
| OCLC Number |
10663121 |
| Subjects |
Environmental health--United States ;
Carcinogens ;
Chemicals--United States ;
Toxicology
|
| Additional Subjects |
Environmental health--United States ;
Carcinogens ;
Chemicals--United States ;
Chemical compounds ;
Toxicology ;
Environmental surveys ;
Exposure ;
Risk ;
Assessments ;
Mixtures ;
Hazardous materials ;
Mathematical models ;
Industrial medicine ;
Public health ;
Humans ;
Malignant neoplasms ;
Toxic substances ;
Cancer ;
Occupational safety and health ;
Pharmacokinetics ;
Path of pollutants ;
Threshold limit valves
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EHAM |
RA1216 EPA-6009-84-008 |
|
Region 1 Library/Boston,MA |
04/29/2016 |
| EJED |
EPA 600/9-84-008 |
|
OCSPP Chemical Library/Washington,DC |
01/01/1988 |
| EKBD |
EPA-600/9-84-008 |
|
Research Triangle Park Library/RTP, NC |
11/18/2005 |
| EKCD |
EPA-600/9-84-008 |
|
CEMM/GEMMD Library/Gulf Breeze,FL |
09/24/2018 |
| ELBD ARCHIVE |
EPA 600-9-84-008 |
|
AWBERC Library/Cincinnati,OH |
09/30/2021 |
| ERAD |
EPA 600/9-84-008 |
|
Region 9 Library/San Francisco,CA |
03/04/2013 |
| ESAD |
EPA 600-9-84-008 |
|
Region 10 Library/Seattle,WA |
03/23/2010 |
| NTIS |
PB84-182369 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
vii, 277 pages : illustrations ; 28 cm |
| Abstract |
The Environmental Criteria and Assessment Office (ECAO) in Cincinnati has developed health risk assessment methods for chronic exposure to single chemical from a single route of exposure. Risk assessments for carcinogens associated an exposure level with a particular incidence of cancer using a non-threshold model which is linear at low doses. For systemic toxicants, the no-observed-adverse-effect level (NOAEL)/Uncertainty Factor approach was used to estimate an acceptable daily intake (ADI). In order to develop methods for assessing risk from exposure to mixtures of chemicals, all relevant routes and all exposure durations must be considered. The basis of the single chemical approach is constantly updated to keep pace with developments in pharmacokinetics, species and route extrapolation, mathematical models, additivity and interaction. These and other relevant issues were addressed during a 2-day workshop on 'Approaches to Risk Assessment for Multiple Chemical Exposures' held by the U.S. Environmental Protection Agency in Cincinnati, Ohio on September 29 and 30, 1982. The workshop was attended by 50 scientists from EPA and private industry. This document presents the results of this workshop, including presentations, critiques and discussion for each of the 11 subtopics covered. |
| Notes |
Distributed to despository libraries in microfiche. "March 1984." Includes bibliographical references. "EPA-600/9-84-008." |
| Place Published |
Cincinnati, OH |
| Supplementary Notes |
Prepared in cooperation with Dynamac Corp., Rockville, MD. |
| Corporate Au Added Ent |
United States. Environmental Protection Agency. Environmental Criteria and Assessment Office (Cincinnati, Ohio) |
| PUB Date Free Form |
1984 |
| NTIS Prices |
PC A13/MF A01 |
| BIB Level |
m |
| Document Type |
BC |
| Medium |
unmediated |
| Content |
text |
| Carrier |
volume |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20210924213023 |
| Language |
eng |
| SUDOCS Number |
EP 1.23/6:600/9-84-008 |
| Origin |
OCLC |
| Type |
MERGE |
| OCLC Rec Leader |
02538cam 2200589Ia 45010 |
